Novartis’s rare cancer drug is launched in the UK

Pharmatimes have reported that Novartis have launched their new drug Jakavi which means for the first time patients in the UK with a rare form of blood cancer will now have access to this targeted therapy

Jakavi (ruxolitinib) is a first-in-class JAK 1 and JAK 2 inhibitor, and is now available to treat patients in the UK with disease-related enlarged spleen or various forms of myelofibrosis, which affects around 0.34-0.76 people in every 100,000.

Myelofibrosis is a rare, potentially life-threatening blood cancer characterised by bone marrow failure, enlarged spleen and debilitating symptoms including extreme fatigue, poor quality of life and weight loss, and shortened survival.

Jakavi received EU approval at the end of August 2012

 

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CK are exhibiting at Pharmsci 2012 Conference

CK Science is proud to announce that we will be exhibiting at Pharmsci 2012 Conference from the 12th of September to the 14th of September 2012 on stand number 30.

 

About Pharma Sci 2012 conference:

Pharmsci 2012 Conference is the premier Pharmaceutical Sciences Conference in the UK organised by the Academy of Pharmaceutical Sciences (APS) taking place at the East Midlands Conference Centre. This year’s conference will showcase the best of pharmaceutical science from the UK and around the world bringing together academic and industrial institutions, providing state of the art technologies and a platform for the development of new pharmaceutical talent.

There will also be presentations on new findings from prestigious leaders and young science researchers on various topics including Polymeric and self-assembled delivery systems, The future of in-vitro drug release testing approaches in product development, Bugs and drugs with a focus on anti-infectives, Tackling counterfeiting by formulation and processing approaches, ‘Green’ formulations and processes, Medicinal chemistry, Biopharmaceutics, Paediatric drug delivery and Inhaled product development.

APS are keen to attract both undergraduate and postgraduate students by offering a programme that develops presentation skills and the scientific networks essential for future careers. There will also be opportunities to network and enhance knowledge for both academic and industrial attendees in a wide range of disciplines.

 

Visit CK Science on stand number 30

So, if you are looking for a new position in the science industry, or are looking to expand your team, please come along to stand 30 to say hello.

We will be happy to help and give advice on finding a new job in the science industry. Or if you would like to add to your current team we will be pleased to talk to with you too.

 

Prize Draw:

You could even be in with a chance of winning a bottle of champagne by entering your business card into our prize draw!

 

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Protein Scientist – Grangemouth

Heather Deagle at CK Science is recruiting for a Protein Scientist for a major biotechnology company based in the Central Belt of Scotland, to work on initially a temporary contract that is very likely to go permanent.

Responsibilities:

As a Protein Scientist the key responsibilities will be too:

  • Develop processes for the conjugation, purification and formulation of antibody conjugates
  • Perform process robustness, characterisation and optimisation studies
  • Process scale up and transfer into our GMP facilities
  • Small scale drug linker synthesis

Qualifications and skills:

The successful candidate for this Protein Scientist role will have following qualifications and experience:

  • a minimum of a BSc degree in Biological/Biochemical Sciences, Chemistry, Engineering or related discipline with good practical lab experience.
  • You will also have experience / awareness of protein purification techniques such as: Chromatography, Filtration and Tangential Flow Filtration (TFF)
  • You will also have Good communication skills, interpersonal skills, ability to work in a fast paced environment.

It would be desirable to have the following skills:

  • Previous biotech industry experience in process development or process scale up / manufacturing.
  • Knowledge of protein modification or conjugation chemistry

How to apply:

Apply online:

For more information or to apply for this Protein Scientist role please contact Heather Deagle on 0191 384 8905 or email hdeagle@ckscience.co.uk. Please quote reference  DH25140 in all correspondence.

 

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4 renewable energy firms in Scotland enter £10 Million energy Saltire challenge

The BBC has reported that two tidal energy and two wave power developers have entered into the race for Scotland’s £10 million Saltire Prize set by government ministers

The Saltire Prize is the largest renewables innovation of its kind. The aim of the competition is to encourage the development of wave and tidal energy devices in Scottish waters. The challenge is for each company to attempt to produce the most electricity over a two-year period, using only the power of the sea.

The four companies are: ScottishPower Renewables, Aquamarine Power, Pelamis Wave Power and MeyGen

Aquamarine Power chief executive, Martin McAdam, said the prize would act as a “global catalyst… bringing together the best brains and financial muscle to crack one of the great challenges of our age”.

 

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Interim Qualified Person, QP – Surrey

Reena Dhana at CK Science is currently recruiting for a Qualified Person (QP) to join a Global Pharmaceutical Company based in Surrey on a full time, 3 month contract.

Responsibilities:

As a Qualified Person you will be responsible for documentation control, sign off and batch release of over the counter drugs.

Qualifications:

The successful candidate for this Qualified Person role will hold a chemistry or pharmacy degree (or equivalent), will be on the register of eligible Qualified Persons and named in the appropriate Manufacturer’s Licence. You will also have experience ideally gained in the Pharmaceutical Industry.

Reena Dhana - Recruiter at CK ScienceHow to apply:

Apply online:

For more information or to apply for this role please contact Reena Dhana on 01438 723 500 or email rdhana@ckscience.co.uk.  Please quote reference ST25093 in all correspondence.

 

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Almac Group launch a NGS service – Northern Ireland

Pharmatimes have reported that the Northern Ireland based Almac Group is introducing a Next Generation Sequencing (NGS) service to expand its solutions supporting the development of personalised medicine.

Almac has said that the service will support Almac’s biopharmaceutical partners in developing molecular tests for enriching clinical trials and establishing companion diagnostics, with a specific focus on targeted re-sequencing,

Professor Paul Harkin, president and md of Almac’s Diagnostics business unit and Professor of Molecular Oncology at Queen’s University Belfast said “There are only a limited number of platforms that are truly amenable to diagnostic delivery. The NGS field has now moved to a point where it is a viable delivery platform and as such is a logical addition to our suite of services”

 

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Automation Engineer – County Limerick

Hannah Milward at CK Science is recruiting for an Senior Automation Engineer x10 to join a medical devices manufacturer based in County Limerick, on a full time, 12 month contract basis.

Responsibilities:

As Senior Automation Engineer, the main purpose of your role will be to develop machine design control systems including servo motion and high speed device integration.

Further responsibilities of this Senior Automation Engineer will include the following:

  • Develop, test and install PLC and control software as part of a highly automated, high volume 24/7 validated production environment 
  • Develop Functional and Detailed Design Specifications from User Requirement Specifications 
  • Develop high quality PLC and HMI code from Functional and Detailed Design Specifications 
  • Work within a cross functional multidisciplinary team environment. 
  • Participates within project teams, provide technical support and make informed decisions on hardware and architecture selection. 
  • Fault-find complex automation equipment 
  • Maintain comprehensive documentation of code to Medical Device standards 
  • Prioritize multiple tasks while working to tight schedules 

Primary Tasks and Responsibilities: 

  • Develop machine control software involving servo pneumatic and data control. 
  • Participate among cross-functional teams to ensure projects are delivered on time and to required quality standards.
  • Develop, debug and validate Control System software programs 
  • Analyse, understand, fault-find and modify automation software

Qualifications and skills:

As Senior Automation Engineer, you will have the following qualifications, skills and experience:

  • Bachelor Degree in Engineering, or equivalent
  • Several years experience working with relevant equipment/systems
  • Strong analytical and problem-solving skills 
  • Ability to organize, plan and execute multiple tasks to tight schedules 
  • Highly motivated self-starter 
  • Ability to document own work clearly and precisely 
  • Strong communication skills    

The job:

As Senior Automation Engineer you will be working with a global medical devices manufacturer based in County Limerick with the following terms:

  • 12 month temporary contract role
  • 8 hours per day, 40 hours per week

HoHannah Milward - Recruiter at CK Sciencew to apply:

Apply online:

For more information or to apply for this Senior Automation Engineer position please contact Hannah Milward on 0114 283 9956 or email hmilward@ckscience.co.uk.  Please quote reference SH25103 in all correspondence.

 

 

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£30m Boost for Biomedical Engineering

As reported by OnMedica, The Wellcome Trust and the Engineering and Physical Sciences Research Council (EPSRC) have announced a joint £30m investment in biomedical engineering with the aim of finding solutions for healthcare problems.

The funding will be available for a limited number of projects which aim to address healthcare problems for which there is no technology which provides an adequate solution. For example, the Science Minister, David Willetts is keen to receive applications for technologies which aim to tackle rare diseases, mental health problems and care for babies and infants. Any successful applications will have access to up to £10m over seven years, as well as the resources to conduct their research.

Universities and Science Minister, David Willetts, said: “Bringing together the UK’s world-class biomedical and physical sciences researchers will be vital in developing the technology to solve our biggest healthcare challenges. This unique initiative supports both basic science and its translation, advancing knowledge and bringing benefits for patients.”

Sir Mark Walport, Director of the Wellcome Trust, said: “The research environment for biomedical engineering in the UK has benefited enormously from the collaboration between EPSRC and the Wellcome Trust, and we are delighted to announce this new initiative, bringing together multidisciplinary teams that will tackle some extremely important medical challenges.”

 

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£30m Boost for Biomedical Engineering   £30m Boost for Biomedical Engineering   £30m Boost for Biomedical Engineering   £30m Boost for Biomedical Engineering

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Dye Company To Double Workforce

Food colouring and dye company ROHA and Simpsons UK Ltd is to double it’s workforce in the next two years, reports the Free Press.

The Monmouthshire based company is a leading manufacturer of dyes for everything from cosmetics to pharmaceuticals and has secured a deal to rent new factory space to increase production and laboratories to improve its research and development sector.

General manager Vika Modi is “delighted to be moving into the new unit” and believes “it was important… to remain in the area to retain [their] skilled workforce.” The premises are to be leased for 15 years and are close by to their existing units.

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London Life Sciences Gets Boost

London’s life sciences industry received a boost as a US company invested £750,000 into a healthcare accelerator fund, reports the Evening Standard.

The US investment firm, Sandbox Industries, launched Healthbox, to give 10 entrepreneurs £75,000 and links to healthcare professionals, investors, retailers, office space and links to the NHS. The enterprise is backed by Bupa and Serco, which runs blood testing laboratories, with mentors coming from across the healthcare professions.

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Liverpool Science Park Receives a Boost in Biomed

The £25 million North West Fund for Biomedical has secured eight desks for start up businesses in the Liverpool Science Park, reports placenorthwest.co.uk.

20 investments have so far been made in innovative bioscience companies who are attempting to get products to market. 40% of the £25 million investment has to be put into Merseyside due to pre-existing agreements. Spark Impact, who manage the investment, will look to help benefit the new companies moving into the Science Park.

Dr Penny Attridge, the senior investment director at Spark, believes that the companies are given an “excellent position to grow their businesses” in an environment where many other biomed companies are located. The life sciences sector, which already employs 4,000 people within Liverpool, is only expected to grow with this further investment.

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Energy Industry Receives Jobs and Investment Boost

A series of investments by oil and gas companies will create thousands of jobs, including the opening of new oil fields in the North Sea, reports the Belfast Telegraph.

There will also be new gas fields, and these new fields should provide 5% of British energy by 2015. The project, called Cygnus, is being led by Centrica and is expected to create 4,000 jobs. BP are also to invest around £60 million in order to improve academic posts across the country.

Vince Cable, the business secretary, said that the “oil and gas industry’s immense contribution to our skills base, industrial capacity and strength as an exporter are pivotal” to the economy, before adding that “collaboration between business and higher education institutions is boosting the status of the UK as a driver of innovation.”

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Analytical Chemist – Aberdeen

Barney Smith is recruiting for an Analytical Chemist to join a company who are global players in the Oil & Gas industry in Aberdeen.

Responsibilities:

The Analytical Chemist role will involve analysis of oil, diesel and drilling fluids using mainly GC although there will be opportunities for working with other instrumentation as and when required.

Qualifications:

The successful candidate for this Analytical Chemist role must be qualified to minimum degree level in chemistry or related subject and ideally have some experience using GC or related instrumentation.  A UK driving licence would also be useful as the role could involve sample collection from remote sites.

The company are global players in the Oil & Gas industry and offer excellent packages and opportunities to progress.

Barney Smith - Manager at CK ScienceHow to apply:

For more information or to apply for this Analytical Chemist position please contact Barney Smith on 0191 384 8905 or email bsmith@ckscience.co.uk.  Please quote reference DH24956 in all correspondence.

 

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GSK,Unilever and Syngenta join alliance as part of the Olympics Global Hunger Summit

The Department of International Development has reported that as part of the Olympic Global Hunger Summit, GSK , Unilever and Syngenta have joined a business alliance to face the growing problem.

The Prime Minister and the Brazilian Vice President, Michel Temer were joined by double Olympic gold medal winner Mo Farah to urge a global drive to boost nutrition.

The two leaders hosted a high-level meeting bringing together representatives from international governments, charities and businesses at Downing Street on the day of the closing ceremony of the London Olympics. They urged the world to take decisive action before the 2016 Olympic Games in Rio to transform the life chances of millions of children by improving their nutrition.

Three new initiatives were announced on these areas, one of these is that some leading UK companies such as Unilever, Syngenta and GSK will work to find ways to make nutritious food available to poor families at prices they can afford.

 

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The London 2012 Olympic are the greenest ever

As reported by the BBC, The Independent Commission for a Sustainable London 2012, has announced that London 2012 has been the greenest Olympics ever.

The commission said that the recycling programmes and regeneration had been a success.

Sustainability was at the heart of London’s bid for the Olympics and the commission said organisers had largely succeeded in achieving it.  For example, the venues were told to be made of at least a quarter recycled materials which included using disused gas pipes in the Olympic Stadium.

The Olympic Park was also praised for regenerating a derelict area and benefiting wildlife

However the commission said much more could be done to minimise the impact of future Olympic Games on people and the planet.

 

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Grapefruit juice provides anti-cancer benefits

As reported by WorldPharmaNews, results of a clinical trial have showed that a glass a day of grapefruit juice lets patients derive the same benefits from an anti-cancer drug as they would get from more than three times as much of the drug by itself.

Researchers at the University of Chicago Medicine study the effects that foods can have on the uptake and elimination of drugs used for cancer treatment.

In the study, they found that eight ounces a day of grapefruit juice can slow the body’s metabolism of a drug called sirolimus, which has been approved for transplant patients but may also help many people with cancer.

Patients who drank eight ounces a day of grapefruit juice increased their sirolimus levels by 350 percent. A drug called ketoconazole that also slows drug metabolism increased sirolimus levels by 500 percent.

The hope is that this combination could help patients avoid side effects associated with high doses of the drug and reduce the cost of the medication.

 

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Quality Manager – County Durham

Heather Deagle at CK Science is recruiting for an experienced Quality Manager or Qualified Person to work in Sterile production for a major pharmaceutical company based in Durham on a temporary basis initially until the end of the year.

Responsibilities:

The mail function of this Quality Manager role is to provide support for the area on managing issues/deviations to free up time for the Batch Release QP to focus on improvements.

As a Quality Manager you will have the following responsibilities:

  • To lead and direct investigative work into products failing to meet requisite standards (and regulatory issues). Also to develop and agree corrective actions arising from such incidents.
  • Lead deviation investigation clinics, coaching where applicable. To lead, prioritize and provide an effective
  • Product Release Service which ensures that all products released for sale or further processing have a quality appropriate to their intended use i.e. comply with Company GMP standards, Product Quality Specifications and Regulatory requirements.
  • Provide GMP advice on an on going basis
  • Support and influence Quality Improvements to reduce rejects, deviations, complaints and increase productivity.

Qualifications and skills:

The successful candidate for this Quality Manager role will have the following qualifications:

  • Qualified Person status
  • Grad (or equivalent) with several years proven post qualification experience in the pharmaceutical or allied industry
  • Experience in handling regulatory affairs
  • Detailed knowledge of current Good Manufacturing Practice requirements within major pharmaceutical markets.

How to apply:

Apply online:

For more information or to apply for this role please contact Heather Deagle on 0191384 8905 or email hdeagle@ckscience.co.uk. Please quote reference DH24906 in all correspondence.

 

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Scotland attracts renewable energy investment

Scottish Development International has reported that Scotland’s growing reputation for the development of pioneering wind, wave and tidal renewable technologies is attracting many major global companies to establish bases in Scotland.

It has been reported that over the last 12 months international companies such as Gamesa, Mitsubishi Power Systems, Samsung Heavy Industries, ABB and Alstom have all announced plans to invest in Scotland to develop renewable technologies.

Gamesa, the Spanish-based international renewables manufacturer has established an R&D facility in Strathclyde, near Glasgow.  This year it announced that Port of Leith, Edinburgh would be the location for the company’s 150 million euro UK offshore wind manufacturing base.

Also the Japanese manufacturing giant Mitsubishi Power Systems plans to invest up to £100 million in Scotland to develop renewable energy research and is also considering creating a major offshore wind turbine manufacturing site.

 

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Shift Chemist – Teesside, UK

Barney Smith at CK Science is recruiting for a Shift Chemist to join a global inspection company to work in an analytical laboratory in Teesside.

Responsibilities:

The Shift Chemist role involves analytical testing of Oil, Gas and Chemicals using GC, GC-MS, AA, IC, UV, IR and wet chemistry. The role will also involve working on site, at heights and in confined spaces.

Qualifications:

As a Shift Chemist you must be qualified to minimum degree level in chemistry or related subject or possess equivalent industrial experience. A flexible approach to working will be required as you will be working around shipping itineraries.

The company:

The company are a global inspection company with offices worldwide.  The company culture is to promote from within so with flexibility on location there will be opportunities to progress your career.

Barney Smith - Manager at CK ScienceHow to apply:

Apply online:

For more information or to apply for these contact Barney Smith on 0191 384 8905 or email bsmith@ckscience.co.uk. Please quote reference DH24897 in all correspondence.

 

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BiFab win a Premier Oil contract creating 350 jobs

The BBC has reported that Burntisland Fabrications (BiFab) has secured a £145 million North Sea oil and gas contract with Premier Oil which will bring around 350 jobs to the Fife area.

The contract involves BiFab constructing both a 3500 tonne topside module and 8000 tonne jacket for Premier Oil’s Solan development west of Shetland.  BiFab will create structures for the platform at its Methil, Burntisland and Arnish yards, as Premier Oil develops its Solan oil field, west of Shetland.

The Solan field is expected to produce about 40 million barrels of oil, with an estimated initial production rate of 24,000 barrels of oil per day from the fourth quarter of 2014.

The contract is due for completion in April 2014 and will create a total of 350 jobs, with around 40 being based at BiFab’s Arnish yard on the Isle of Lewis.

 

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